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The study aims to enhance understanding by investigating clinical presentation, diagnosis, treatment, complications, and prognoses in adult PIL cases. Research methods. The research …

Nov 21, 2023 · Pollack and colleagues reported a case of PIL in a female patient with tuberous sclerosis complex (TSC) and a TSC2 mutation. A trial of the mTOR inhibitor rapamycin …

We aimed to introduce the action mechanism of each drug and treatment overview in a single-center experience and a review of the literature on second-line therapy for primary intestinal …

Aug 27, 2023 · A 30-year-old woman with past medical history of primary intestinal lymphangiectasia (PIL), hypothyroidism, and well-controlled asthma was evaluated in our …

May 12, 2019 · Serial evaluation and longitudinal follow up of patient samples under eculizumab (anti-complement C5 antibody) therapy investigates dynamic alterations in the pathological …

Jun 4, 2014 · Researchers want to look for a relationship between lymphatic disorders and variations of certain genes found in the lung, blood, and other places in the body. Objective: - …

To find the right clinical study we recommend you consult your doctors, other trusted medical professionals, and patient organizations. Additionally, you can use ClinicalTrials.gov to search …

Feb 6, 2024 · Clinical and laboratory characteristics were evaluated. Results: Of 53 patients evaluated, 69,8% with Crohn’s disease (CD) and 30.2% with ulcerative colitis (UC).

We describe a rare case of primary intestinal lymphangiectasia and highlight its clinical presentation, diagnosis, and treatment. rimary intestinal lymphangiectasia, also known as …

Management of intestinal lymphangiectasia includes the replacement of long-chain fatty acids in the diet with medium-chain triglycerides to reduce intestinal protein losses. Meet a team of …

Intestinal lymphangiectasia (IL) is a rare disease characterized by a dilatation of the intestinal lymphatics and loss of lymph fluid into the gastrointestinal tract leading to hypoproteinemia, …

We compared and analyzed all endoscopic images, classified them into four types according to the endoscopic features of the intestinal mucosa, and analyzed the post-lymphographic …

Feb 27, 2025 · The trial was conducted in accordance with the principles of the Declaration of Helsinki and the International Conference on Harmonisation Good Clinical Practice guidelines. …

5 days ago · Objective To summarize the existing evidence from double-blind randomized controlled trials (RCTs) and cohort studies regarding the effects of biologic agents for the …

Mar 5, 2025 · Design, Setting, and Participants Prospective, randomized, open-blinded end point clinical trial in 7 hospitals across Australia (between 2013 and 2020; the last date of follow-up …

4 days ago · The two randomized controlled trials included were assessed as having a low risk of bias using the RoB 2 tool (Figure S1B). 3.2 Clinical Improvement Extremity Lymphedema. The …

Feb 27, 2025 · BACKGROUND: Endovascular therapy (EVT) has been proven effective for patients with acute ischemic stroke with large infarcts. This study aimed to explore the impact …

Mar 6, 2025 · HARMONi-2, a randomised, double-blind, phase 3 multicentre trial conducted in China, is the first trial to evaluate a novel agent (ivonescimab) against an anti-PD-1 ICI …

Primary intestinal lymphangiectasia (PIL), first described in 1961, is a rare disorder of unknown etiology resulting in protein-losing enteropathy. The disease is characterized by dilatation and …

3 days ago · The STOMP study was conducted by the NIH-funded ACTG, a global clinical trials network focused on HIV and other infectious diseases. SIGA Technologies, Inc., based in New …

Aug 16, 2024 · These trials were registered at ClinicalTrials.gov (identifier: NCT01452646) and EudraCT (identifier: 2010-023809-36). The patients’ risk assignment incorporated pretreatment …

In this study, we define the lymphatic phenotype and clinical course of 4 individuals with CCLA identified to express somatic pathogenic KRAS variants, including 3 with epidermal nevus …

4 days ago · The Phase 3 VERITAC-2 clinical trial (NCT05654623) is a global randomized study evaluating the efficacy and safety of vepdegestrant (ARV-471) as a monotherapy compared to …

Several signaling pathways have been revealed to be involved in the progression and development of lymphangioma, and specific inhibitors targeting these pathways have been …